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課程名稱 |
生理之輸送現象
Transport Phenomena in Physiolgical Systems |
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開課學期 |
101-1 |
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授課對象 |
工學院 化學工程學系 |
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授課教師 |
蔡偉博 |
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課號 |
ChemE5009 |
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課程識別碼 |
524 U0470 |
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班次 |
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學分 |
3 |
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全/半年 |
半年 |
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必/選修 |
選修 |
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上課時間 |
星期二7,8,9(14:20~17:20) |
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上課地點 |
普301 |
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備註 |
化工選修課程。與王勝仕合開
總人數上限：60人 |
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Ceiba 課程網頁 |
http://ceiba.ntu.edu.tw/1011biotransport |
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課程簡介影片 |
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核心能力關聯 |
核心能力與課程規劃關聯圖 |
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課程大綱
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為確保您我的權利,請尊重智慧財產權及不得非法影印
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課程概述 |
1.Physical properties of the body fluids and the cell membrane
a.Body fluids and fluid compositions
b.Osmotic pressure and osmolarity
c.The cell membrane
d.Solute transport in biological systems
2.Elements of fluid mechanics: rheology of blood
a.Momentum, mass and energy balances
b.Fluid rheology
c.Dimensional analysis and scaling
d.The flow properties of blood
3.Fundamental of Mass Transport: Oxygen transport in biological systems
a.Introduction of diffusion concepts
b.Conservation mass
c.Convection/diffusion equation
d.Membrane transport
e.Oxygen transport
4.Pharmacokinetic analysis
a.Differential transport equation
i.Diffusion without reaction
ii.Diffusion with reaction
b.Entry routes for drugs
c.Factors that affect drug distribution
d.First-order drug absorption and elimination
5.Applications in extracorporeal devices
a.Membrane solute transport
b.Estimating the mass-transfer coefficients
c.Estimating the solute diffusivity in blood
d.Hemodialysis
e.Immobilized enzyme reactors
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課程目標 |
Teach students transport of fluid and mass in the human body. The students will be expected to solve detailed biomedical related problems in fluid and mass transport. Topics to be covered include biological and artificial membranes, body fluids, the physical and flow properties of blood, tissue oxygen transport, pharmacokinetics, and applications in the extracorporeal devices and tissue engineering. |
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課程要求 |
No requirement |
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預期每週課後學習時數 |
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Office Hours |
另約時間 |
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指定閱讀 |
以上課內容與講義為主 |
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參考書目 |
1.Basic transport phenomena in biomedical engineering / Ronald L. Rournier,
Edward Brothers, Lillington, NC, 1998.
2.Transport phenomena 2nd edition / Bird, Stewart and Lightfoot, John Wiley
& Sons Inc., 2
3. Biomedical Engineering Principles / D. O. Cooney, Marcel Dekker, 1976
4. Medical physiology / R. A. Rhoades and G. A. Tanner, Little, Brown and
Company, 1995.
5. Literature
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評量方式
(僅供參考) |
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No. |
項目 |
百分比 |
說明 |
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1. |
期中考 |
30% |
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2. |
期末考 |
30% |
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3. |
作業 |
15% |
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4. |
期末報告（書面） |
15% |
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5. |
期末報告（口頭） |
10% |
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週次 |
日期 |
單元主題 |
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第1週 |
9/11 |
Introdcution_王勝仕 |
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第2週 |
9/18 |
The Physical and Flow Properties of Blood_蔡偉博 |
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第3週 |
9/25 |
The Physical and Flow Properties of Blood_蔡偉博
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第4週 |
10/2 |
Cell membrane transport and interstitial fluid filtration_蔡偉博 |
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第5週 |
10/9 |
Cell membrane transport and interstitial fluid filtration_蔡偉博 |
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第6週 |
10/16 |
Solute Transport in Biological System_蔡偉博 |
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第7週 |
10/23 |
Solute Transport in Biological System_蔡偉博 |
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第8週 |
10/30 |
Oxygen Transport in Biological Systems_王勝仕 |
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第9週 |
11/6 |
期中考 |
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第10週 |
11/13 |
Oxygen Transport in Biological Systems_王勝仕 |
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第11週 |
11/20 |
Pharmacokinetic Analysis_王勝仕 |
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第12週 |
11/27 |
Pharmacokinetic Analysis_王勝仕 |
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第13週 |
12/4 |
Extracorporeal Devices_王勝仕 |
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第14週 |
12/11 |
Extracorporeal Devices_王勝仕 |
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第15週 |
12/18 |
期末報告 |
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第16週 |
12/25 |
期末報告 |
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第17週 |
1/1 |
元旦放假 |
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第18週 |
1/8 |
期末考 |
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